133 Nobuyuki Kimura 8 }iabetes-Related Dementia. 103 Yanxing Chen, Qian Yu, and Cheng-Xin Gong 7 Type II Diabetes Mellitus Accelerates Age-Dependent Aβ Pathology in Cynomolgus Monkey Brain. 85 Mitsuru Shinohara and Naoyuki Sato 6 Molecular Connection Between Diabetes and Dementia. de la Monte 5 The Roles of Apolipoprotein E, Lipids, and Glucose in the Pathogenesis of Alzheimer’s Disease.
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27 Yusaku Nakabeppu 4 The Full Spectrum of Alzheimer’s Disease Is Rooted in Metabolic Derangements That Drive Type 3 Diabetes. 13 Toshiharu Ninomiya 3 Molecular Pathophysiology of Insulin Depletion, Mitochondrial Dysfunction, and Oxidative Stress in Alzheimer’s Disease Brain. 1 Yusaku Nakabeppu 2 ~pidemiological Evidence of the Relationship Between Diabetes and Dementia. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singaporeġ Origins of Brain Insulin and Its Function. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication.
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in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The use of general descriptive names, registered names, trademarks, service marks, etc. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed.
Toshiharu Ninomiya Department of Epidemiology and Public Health, Graduate School of Medical Sciences Kyushu University Fukuoka, Japan Yusaku Nakabeppu Toshiharu Ninomiya EditorsĪdvances in Experimental Medicine and Biology Editorial Board: IRUN R. COHEN, The Weizmann Institute of Science, Rehovot, Israel ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA JOHN D. LAMBRIS, University of Pennsylvania, Philadelphia, PA, USA RODOLFO PAOLETTI, University of Milan, Milan, Italy NIMA REZAEI, Tehran University of Medical Sciences, Tehran, Iranĭiabetes Mellitus A risk factor for Alzheimer’s DiseaseĮditors Yusaku Nakabeppu Division of Neurofunctional Genomics, Department of Immunobiology and Neuroscience Medical Institute of Bioregulation, Kyushu University Fukuoka, Japan Therapeutic Strategies for Alzheimer’s Disease in the View of Diabetes Mellitus (Yasumasa Ohyagi, Katsue Miyoshi, Norimichi Nakamura).Pages 227-248 Citation previewĪdvances in Experimental Medicine and Biology 1128 Mammalian Target of Rapamycin at the Crossroad Between Alzheimer’s Disease and Diabetes (Hanyu Liang, Jia Nie, Candice E. Tortuous Paths of Insulin Signaling and Mitochondria in Alzheimer’s Disease (Cristina Carvalho, Susana M. Type II Diabetes Mellitus Accelerates Age-Dependent Aβ Pathology in Cynomolgus Monkey Brain (Nobuyuki Kimura).Pages 133-145ĭiabetes-Related Dementia (Haruo Hanyu).Pages 147-160 Molecular Connection Between Diabetes and Dementia (Yanxing Chen, Qian Yu, Cheng-Xin Gong).Pages 103-131 The Roles of Apolipoprotein E, Lipids, and Glucose in the Pathogenesis of Alzheimer’s Disease (Mitsuru Shinohara, Naoyuki Sato).Pages 85-101
The Full Spectrum of Alzheimer’s Disease Is Rooted in Metabolic Derangements That Drive Type 3 Diabetes (Suzanne M. Molecular Pathophysiology of Insulin Depletion, Mitochondrial Dysfunction, and Oxidative Stress in Alzheimer’s Disease Brain (Yusaku Nakabeppu).Pages 27-44 Origins of Brain Insulin and Its Function (Yusaku Nakabeppu).Pages 1-11Įpidemiological Evidence of the Relationship Between Diabetes and Dementia (Toshiharu Ninomiya).Pages 13-25
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